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Article

Computational genetic mapping in mice: the ship has sailed.

Science translational medicine - 21 Oct 2009

Zheng Ming, Shafer Steve, Liao Guochun, Liu Hong-Hsing, Peltz Gary

Abstract excerpt

Computational haplotype-based genetic mapping can be used to discover new biological mechanisms, disease-related pathways, and unexpected uses for existing drugs. Here we discuss the benefits and limitations of this methodology, its impact on translational medicine, and its future course.

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Identifiers

PMID: 20368166
DOI: 10.1126/scitranslmed.3000377

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