Factor V Cambridge: a new mutation (Arg306-->Thr) associated with resistance to activated protein C.

Article

Factor V Cambridge: a new mutation (Arg306-->Thr) associated with resistance to activated protein C.

Blood - 15 Feb 1998

Williamson D, Brown K, Luddington R, Baglin C, Baglin T

Abstract excerpt

A new factor V mutation associated with resistance to activated protein C and thrombosis (factor V Cambridge, Arg306-->Thr) was found in one patient from a carefully selected group of 17 patients with venous thrombosis and confirmed APC resistance in the absence of the common Gln506 mutation. The...

Topics

Arginine
Drug Resistance
Factor V
Humans
Mutation
Protein C
Thrombosis

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