Article
Resistance to activated protein C caused by a factor V gene mutation.
Current opinion in hematology - 1 Sept 1995
Zöller B, Dahlbäck B
Abstract excerpt
Each year, approximately one in 1000 individuals suffers from venous thromboembolism. The pathogenesis of the disease is multifactorial and a thrombotic event is the result of a combination of genetic and circumstantial risk factors. Until recently, genetic defects could only be identified in a minority of thrombosis patients. The discovery of inherited resistance to activated protein C as a risk factor for...
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