Inherited resistance to activated protein C caused by presence of the FV:Q506 allele as a basis of venous thrombosis.

doi:10.1159/000217311

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Article

Inherited resistance to activated protein C caused by presence of the FV:Q506 allele as a basis of venous thrombosis.

Haemostasis - 1 Oct 1996

Dahlbäck B, Zöller B, Hillarp A

Abstract excerpt

Inherited resistance to activated protein C (APC) was recently discovered as a cause of familial thrombophilia and is now known to be the most common genetic risk factor for venous thrombosis. In a majority of cases, APC resistance is associated with a single point mutation in the factor V gene,...

Topics

Adolescent
Blood Coagulation Tests
Child
Disease Susceptibility
Enzyme Activation
Factor V
Factor V Deficiency
Female
Genotype
Humans
Male
Phenotype
Point Mutation
Pregnancy
Pregnancy Complications, Hematologic
Protein C
Protein S Deficiency
Risk Factors

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