Article
Factor V Arg306-->Thr (factor V Cambridge) and factor V Arg306-->Gly mutations in venous thrombotic disease.
British journal of haematology - 1 Dec 1998
Franco R F, Maffei F H, Lourenço D, Morelli V, Thomazini I A, Piccinato C E, Tavella M H, Zago M A
Abstract excerpt
We investigated the prevalence of two reported mutations of the factor V gene (factor V Arg306-->Thr, or factor V Cambridge, and factor V Arg306-->Gly) in 104 relatively young patients with verified venous thrombosis and in 208 age-, sex- and race-matched controls, in order to establish whether t...
Topics
- Adolescent
- Adult
- Amino Acid Substitution
- Child
- Child, Preschool
- Factor V
- Female
- Genetic Predisposition to Disease
- Humans
- Infant
- Male
- Middle Aged
- Mutation
- Risk Factors
- Venous Thrombosis