Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative methods of attenuating Salmonella species for potential vaccine use.

Research in microbiology - 1 Jan 2000

Wilson D R, Chatfield S, Betts J, Griffiths A, Leung K Y, Dougan G, Finlay B B

Abstract excerpt

Because of their invasive properties, Salmonella species are uniquely suited for use as live oral vaccines, and mutants attenuated in general metabolic functions show promise as vaccine strains. We have identified a Salmonella choleraesuis transposon mutant which is deficient in abilities to attach to, invade or penetrate through animal cells. This mutant is avirulent in mice, yet is able to persist within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Vaccines
Share to DNA Transposable Elements
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mutation

Share to Salmonella

Share to Vaccines, Attenuated

Share to Vaccines, Synthetic

Source

Identifiers

PMID: 1966254
DOI: 10.1016/0923-2508(90)90117-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative methods of attenuating Salmonella species for potential vaccine use.PMID 1966254Read ↗

Oral immunization using live attenuated Salmonella spp. as carriers of foreign antigens.Semantic proximity Read ↗

Vaccines to Control Salmonella in PoultrySemantic proximity Read ↗

Live oral avirulent Salmonella vaccines.Semantic proximity Read ↗

In-vitro and in-vivo characteristics of TnphoA mutant strains of Salmonella serotype Gallinarum not invasive for tissue culture cells.Semantic proximity Read ↗

Identification of Salmonella enterica serovar Enteritidis mutants overproducing OMVs as vaccine candidates.Semantic proximity Read ↗

Genetic engineering of Salmonella spp. for novel vaccine strategies and therapeuticsSemantic proximity Read ↗

Live attenuated Salmonella: a paradigm of mucosal vaccinesSemantic proximity Read ↗

Genetic determinants of Salmonella enterica critical for attachment and biofilm formation.Semantic proximity Read ↗

High-throughput screening for salmonella avirulent mutants that retain targeting of solid tumors.Semantic proximity Read ↗

Killed but metabolically active Salmonella typhimurium: application of a new technology to an old vector.Semantic proximity Read ↗

Contribution of proton-translocating proteins to the virulence of Salmonella enterica serovars Typhimurium, Gallinarum, and Dublin in chickens and mice.Semantic proximity Read ↗

A Live Oral Fowl Typhoid Vaccine with Reversible O-Antigen Production.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.