Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunogenicity of Bacillus anthracis protective antigen domains and efficacy of elicited antibody responses depend on host genetic background.

Clinical and vaccine immunology : CVI - 1 Jul 2008

Abboud Nareen, Casadevall Arturo

Abstract excerpt

Neutralizing antibodies to Bacillus anthracis protective antigen (PA), a component of anthrax toxin, mediate protection against anthrax. PA is antigenically complex and can elicit protective and nonprotective antibodies. Furthermore, vaccinated individuals demonstrate considerable variability in their antibody responses to PA. To explore the relationship between PA structure and antigenicity, we produced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthrax
Share to Antibodies, Bacterial
Share to Antigens, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bacillus anthracis

Share to Bacterial Toxins

Share to Epitopes, B-Lymphocyte

Share to Neutralization Tests

Share to Vaccination

Source

Open in PubMed Open full text

Identifiers

PMID: 18480236
DOI: 10.1128/CVI.00015-08
PMCID: PMC2446646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunogenicity of Bacillus anthracis protective antigen domains and efficacy of elicited antibody responses depend on host genetic background.PMID 18480236Read ↗

Protective immunity induced by Bacillus anthracis toxin-deficient strains.Semantic proximity Read ↗

HLA class II polymorphism influences the immune response to protective antigen and susceptibility to <i>Bacillus anthracis</i>Semantic proximity Read ↗

Immunization against anthrax with aromatic compound-dependent (Aro-) mutants of Bacillus anthracis and with recombinant strains of Bacillus subtilis that produce anthrax protective antigen.Semantic proximity Read ↗

Vaccine protection against Bacillus cereus-mediated respiratory anthrax-like disease in mice.Semantic proximity Read ↗

Genetic diversity in the protective antigen gene of Bacillus anthracis.Semantic proximity Read ↗

Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax.Semantic proximity Read ↗

Anthrax vaccines.Semantic proximity Read ↗

Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection.Semantic proximity Read ↗

Identification of new dominant-negative mutants of anthrax protective antigen using directed evolution.Semantic proximity Read ↗

Selection and evaluation of the immunogenicity of protective antigen mutants as anthrax vaccine candidates.Semantic proximity Read ↗

Identifying protective antigens of Staphylococcus aureus, a pathogen that suppresses host immune responses.Semantic proximity Read ↗

Antibodies against In Vivo-Expressed Antigens Are Sufficient To Protect against Lethal Aerosol Infection with Burkholderia mallei and Burkholderia pseudomallei.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.