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Article

Pathogenicity island 2 mutants of Salmonella typhimurium are efficient carriers for heterologous antigens and enable modulation of immune responses.

Infection and immunity - 1 Mar 1999

Medina E, Paglia P, Nikolaus T, Müller A, Hensel M, Guzmán C A

Abstract excerpt

The potential use as vaccine delivery system of Salmonella typhimurium strains harboring defined mutations in the sseC (HH104) and sseD (MvP101) genes, which encode putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2, was evaluated and compared with that of the well-characterized aroA mutant strain SL7207 by using beta-galactosidase (beta-Gal) as a model antigen. When...

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Identifiers

PMID: 10024548
DOI: 10.1128/IAI.67.3.1093-1099.1999
PMCID: PMC96434

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Source receipt: pubmed, retrieved 7 Sept 2026.

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