Article
The Srk1 protein kinase is a target for the Sty1 stress-activated MAPK in fission yeast.
The Journal of biological chemistry - 6 Sept 2002
Smith Deborah A, Toone W Mark, Chen Dongrong, Bahler Jurg, Jones Nic, Morgan Brian A, Quinn Janet
Abstract excerpt
The fission yeast stress-activated Sty1/Spc1 MAPK pathway responds to a similar range of stresses as do the mammalian p38 and SAPK/JNK MAPK pathways. In addition, sty1(-) cells are sterile and exhibit a G(2) cell cycle delay, indicating additional roles of Sty1 in meiosis and cell cycle progression. To identify novel proteins involved in stress responses, a microarray analysis of the Schizosaccharomyces pombe...
Topics
- Active Transport, Cell Nucleus
- Amino Acid Motifs
- Amino Acid Sequence
- Blotting, Western
- Cell Nucleus
- Flow Cytometry
- Fungal Proteins
- G1 Phase
- G2 Phase
- Hydrogen Peroxide
- MAP Kinase Signaling System
- Meiosis
- Mitogen-Activated Protein Kinase Kinases