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Article

Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.

Genes & development - 1 Sept 1995

Millar J B, Buck V, Wilkinson M G

Abstract excerpt

Simultaneous inactivation of pyp1 and pyp2 PTPases in fission yeast leads to aberrant cell morphology and growth arrest. Spontaneous recessive mutations that bypass the requirement for pyp1 and pyp2 and reside in two complementation groups were isolated, sty1 and sty2. sty1- and sty2- mutant cells are substantially delayed in the timing of mitotic initiation. We have isolated the sty1 gene, which encodes a MAP...

Topics

Amino Acid Sequence
Base Sequence
Cell Cycle Proteins
Enzyme Induction
Gene Expression Regulation, Fungal
Genes, Fungal
Humans
Mitogen-Activated Protein Kinase Kinases
Mitogen-Activated Protein Kinases
Mitosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Osmolar Concentration

Phosphorylation

Protein Kinases

Protein Serine-Threonine Kinases

Protein Tyrosine Phosphatases

Schizosaccharomyces

Source

Identifiers

PMID: 7657164
DOI: 10.1101/gad.9.17.2117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7657164-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.PMID 7657164Read ↗

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