Article
The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.
Genes & development - 15 Sept 1996
Wilkinson M G, Samuels M, Takeda T, Toone W M, Shieh J C, Toda T, Millar J B, Jones N
Abstract excerpt
The atf1+ gene of Schizosaccharomyces pombe encodes a bZIP transcription factor with strong homology to the mammalian factor ATF-2. ATF-2 is regulated through phosphorylation in mammalian cells by the stress-activated mitogen-activated protein (MAP) kinases SAPK/JNK and p38. We show here that the fission yeast Atf1 factor is also regulated by a stress-activated kinase, Sty1. The Sty1 kinase is stimulated by a...
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