Article
Activation of shaker potassium channels. I. Characterization of voltage-dependent transitions.
The Journal of general physiology - 1 Feb 1998
Schoppa N E, Sigworth F J
Abstract excerpt
The conformational changes associated with activation gating in Shaker potassium channels are functionally characterized in patch-clamp recordings made from Xenopus laevis oocytes expressing Shaker channels with fast inactivation removed. Estimates of the forward and backward rates for transition...
Topics
- Animals
- Biotransformation
- Electrophysiology
- Ion Channel Gating
- Kinetics
- Membrane Potentials
- Mice
- Mice, Neurologic Mutants
- Mutation
- Oocytes
- Patch-Clamp Techniques
- Potassium Channels
- Xenopus laevis