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Article

Resolving the gating charge movement associated with late transitions in K channel activation.

Biophysical journal - 1 Aug 2001

Loboda A, Armstrong C M

Abstract excerpt

We examined the late transitions in the activation sequence of potassium channels by analyzing gating currents of mutant Shaker IR channels and using the potassium channel blocker 4-aminopyridine (4AP). Gating currents were recorded from a double mutant of Shaker that was nonconducting (W434F mutation) and had the late gating transitions shifted to the right on the voltage axis (L382C mutation), thus separating...

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Identifiers

PMID: 11463634
DOI: 10.1016/S0006-3495(01)75750-5
PMCID: PMC1301562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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