Article
Activation of Shaker potassium channels. II. Kinetics of the V2 mutant channel.
The Journal of general physiology - 1 Feb 1998
Schoppa N E, Sigworth F J
Abstract excerpt
This second of three papers, in which we functionally characterize activation gating in Shaker potassium channels, focuses on the properties of a mutant channel (called V2), in which the leucine at position 382 (in the Shaker B sequence) is mutated to valine. The general properties of V2's ionic and gating currents are consistent with changes in late gating transitions, in particular, with V2 disrupting the...
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