Article
Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine.
Annals of medicine - 1 Jan 2007
Goyette Philippe, Labbé Catherine, Trinh Truc T, Xavier Ramnik J, Rioux John D
Abstract excerpt
Crohn's disease (CD) and ulcerative colitis (UC), also known as inflammatory bowel diseases (IBD), are characterized by chronic inflammation of the gastrointestinal tract. IBD is among the few complex diseases for which several genomic regions and specific genes have been identified and confirmed in multiple replication studies. We will review the different loci implicated in disease risk in the context of three...
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