Article
Novel susceptibility genes in inflammatory bowel disease.
World journal of gastroenterology - 7 Apr 2006
Noble Colin, Nimmo Elaine, Gaya Daniel, Russell Richard K, Satsangi Jack
Abstract excerpt
The inflammatory bowel disease, Crohn's disease and ulcerative colitis, are polygenic disorders with important environmental interactions. To date, the most widely adopted approach to identifying susceptibility genes in complex diseases has involved genome wide linkage studies followed by studies of positional candidate genes in loci of interest. This review encompasses data from studies into novel candidate...
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