An improved assembly assay for peptide binding to HLA-B*2705 and H-2K(k) class I MHC molecules.

doi:10.1016/s0022-1759(97)00142-7

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Article

An improved assembly assay for peptide binding to HLA-B*2705 and H-2K(k) class I MHC molecules.

Journal of immunological methods - 10 Nov 1997

Tan L, Andersen M H, Elliott T, Haurum J S

Abstract excerpt

The assembly assay for peptide binding to class I major histocompatibility complex (MHC) is based on the ability to stabilise MHC class I molecules from mutant cell lines by the addition of suitable peptides. Such cell lines lack a functional transporter associated with antigen presentation (TAP)...

Topics

Amino Acid Sequence
Cell Line
Epitopes
H-2 Antigens
HLA-B Antigens
Humans
Oligopeptides
Phenotype
Protein Binding

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