Article
Effect of a tapasin mutant on the assembly of the mouse MHC class I molecule H2-K(d).
Immunology and cell biology - 1 Jan 2010
Simone Laura C, Wang Xiaojian, Tuli Amit, Solheim Joyce C
Abstract excerpt
Major histocompatibility complex (MHC) class I heavy chain/beta(2)m heterodimers assemble with antigenic peptides through interactions with peptide-loading complex proteins, including tapasin and ERp57. In human cells, a cysteine residue within tapasin (C95) has been shown to form a covalent bond...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
