Article
Inhibition of HIV replication by capsid mutant C6b.
Biochemical and biophysical research communications - 14 Jan 1998
Shimano R, Iida S, Fukumori T, Yamamoto Y, Kawamura M, Furuta R A, Adachi A
Abstract excerpt
A Gag capsid mutant of human immunodeficiency virus type 1 (HIV-1) designated C6b was biologically and biochemically characterized with respect to its ability to suppress the replication of wild-type (wt) HIV. The C6b efficiently interfered with the replication of wt HIV-1 in the cleavage of Gag precursor, and also in the early replication process before or during viral DNA synthesis after viral penetration. The...
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