Article
Effects of blocking individual maturation cleavages in murine leukemia virus gag.
Journal of virology - 1 Feb 2004
Oshima Masamichi, Muriaux Delphine, Mirro Jane, Nagashima Kunio, Dryden Kelly, Yeager Mark, Rein Alan
Abstract excerpt
A single protein, termed Gag, is responsible for retrovirus particle assembly. After the assembled virion is released from the cell, Gag is cleaved at several sites by the viral protease (PR). The cleavages catalyzed by PR bring about a wide variety of physical changes in the particle, collective...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
