Article
Mutational analysis of the C-terminal gag cleavage sites in human immunodeficiency virus type 1.
Journal of virology - 1 Sept 2007
Coren Lori V, Thomas James A, Chertova Elena, Sowder Raymond C, Gagliardi Tracy D, Gorelick Robert J, Ott David E
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) Gag is expressed as a polyprotein that is cleaved into six proteins by the viral protease in a maturation process that begins during assembly and budding. While processing of the N terminus of Gag is strictly required for virion maturation and infectivi...
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