Article
Renal manifestations in angiotensinogen-deficient mice: unexpected phenotypes emerge.
Experimental nephrology - 1 Jan 2000
Nagata M, Murakami K, Watanabe T
Abstract excerpt
The divergence between previously suggested RAS functions and unexpected phenotypes in RAS-related knockout mice may provide some hints about unknown functions of the RAS. One unsolved question is: does angiotensin II act directly as a growth factor for the renal cells via its specific receptors, or regulate some factor(s) responsible for renal cell growth? Advanced technology may help to answer this question and...
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