Article
The renin-angiotensin system in the development of the congenital anomalies of the kidney and urinary tract.
Current opinion in pediatrics - 1 Apr 2006
Niimura Fumio, Kon Valentina, Ichikawa Iekuni
Abstract excerpt
PURPOSE OF REVIEW: Recognition of the dramatically expanded functional repertoire of the renin-angiotensin system now includes a role in morphogenesis of the kidney and urinary tract. On the basis of published data, the article presents formulations of mechanisms through which the system operates. RECENT FINDINGS: Studies in humans and animals carrying defective angiotensin-related genes have provided unequivocal...
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