Article

In hypertension, the kidney is not always the heart of the matter

2005-04-01

Abstract excerpt

Blood pressure abnormalities are thought to originate from intrinsic changes in the kidney, a concept that has been largely unchallenged for more than 4 decades. However, recent molecular, cellular, and transgenic mouse studies support an alternative hypothesis: primary abnormalities in vascular cell function can also directly cause abnormalities of blood pressure. In this issue of the JCI, Crowley and coworkers d...

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Literature Corpus work: 1e763783-7008-5bb8-b050-10e3b35f9440
DOI: 10.1172/jci200524806

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