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A review: simulation tools for genome-wide interaction studies.

Briefings in functional genomics - 6 Dec 2024

Shang Junliang, Xu Anqi, Bi Mingyuan, Zhang Yuanyuan, Li Feng, Liu Jin-Xing

Abstract excerpt

Genome-wide association study (GWAS) is essential for investigating the genetic basis of complex diseases; nevertheless, it usually ignores the interaction of multiple single nucleotide polymorphisms (SNPs). Genome-wide interaction studies provide crucial means for exploring complex genetic interactions that GWAS may miss. Although many interaction methods have been proposed, challenges still persist, including...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39173096
DOI: 10.1093/bfgp/elae034

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