Article
Association of posterior p-values of S.A.G.E. SIBPAL proportion-IBD and Haseman-Elston statistics for ACTHR112.
Genetic epidemiology - 1 Jan 1997
Gordon D, Finch S J, Jacobs A L, Mendell N R, Single R M, Marr T G
Abstract excerpt
A common practice among researchers performing linkage studies is the use of equal allele frequencies as input when reporting p-values from computer linkage programs such as S.A.G.E. SIBPAL. Our results, using 5,000 sets from a uniform-prior distribution of allele frequencies, showed that such input may be problematic. Further, we found that the S.A.G.E. SIBPAL test for proportion of alleles shared identical by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.