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Article

The most primitive vertebrates with jaws possess highly polymorphic MHC class I genes comparable to those of humans.

Immunity - 1 Dec 1997

Okamura K, Ototake M, Nakanishi T, Kurosawa Y, Hashimoto K

Abstract excerpt

We report the isolation and extensive analysis of highly polymorphic MHC class I genes from sharks (Triakis scyllia), which belong to the most primitive vertebrate group with jaws, the cartilaginous fish. Predicted complete peptide-binding domains showed retention of the critical amino acid resid...

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Identifiers

PMID: 9430223
DOI: 10.1016/s1074-7613(00)80396-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9430223-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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