Article
Classical MHC class I genes composed of highly divergent sequence lineages share a single locus in rainbow trout (Oncorhynchus mykiss).
Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2002
Aoyagi Kazuhiko, Dijkstra Johannes M, Xia Chun, Denda Ikuo, Ototake Mitsuru, Hashimoto Keiichiro, Nakanishi Teruyuki
Abstract excerpt
The classical MHC class I genes have been known to be highly polymorphic in various vertebrates. To date, putative allelic sequences of the classical MHC class I genes in teleost fish have been reported in several studies. However, the establishment of their allelic status has been hampered in most cases by the lack of appropriate genomic information. In the present study, using heterozygous and homozygous fish,...
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