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Article

Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment.

Current biology : CB - 1 Jan 1998

Yang J, Symes K, Mercola M, Schreiber S L

Abstract excerpt

BACKGROUND: Receptor tyrosine kinases (RTKs) regulate the proliferation, differentiation and metabolism of cells, and play key roles in tissue repair, tumorigenesis and development. To facilitate the study of RTKs, we have made conditional alleles that encode monomeric forms of the normally heterotetrameric insulin receptor and monomeric platelet-derived growth factor (PDGF) beta receptors fused to the...

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Source

Identifiers

PMID: 9427627
DOI: 10.1016/s0960-9822(98)70015-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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