Article
Effect of a mutation in the anticodon of human mitochondrial tRNAPro on its post-transcriptional modification pattern.
Nucleic acids research - 15 Jan 1998
Brulé H, Holmes W M, Keith G, Giegé R, Florentz C
Abstract excerpt
Although the gene sequences of all 22 tRNAs encoded in the human mitochondrial genome are known, little information exists about their sequences at the RNA level. This becomes a crucial limitation when searching for a molecular understanding of the growing number of maternally inherited human diseases correlated with point mutations in tRNA genes. Here we describe the sequence of human mt-tRNAPropurified from...
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