Article
Reliability of a flushing questionnaire and the ethanol patch test in screening for inactive aldehyde dehydrogenase-2 and alcohol-related cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 1997
Yokoyama A, Muramatsu T, Ohmori T, Kumagai Y, Higuchi S, Ishii H
Abstract excerpt
Molecular epidemiology of esophageal and upper aerodigestive tract cancers revealed that alcohol is more carcinogenic in persons with inactive aldehyde dehydrogenase-2 (ALDH2) than in those with active ALDH2. A simple questionnaire has been developed to screen for the facial flushing that occurs in persons with inactive ALDH2 when they drink even a single glass of beer. In this study, 266 of 284 consecutive male...
Topics
- Aged
- Alcohol Drinking
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Biomarkers
- Ethanol
- Flushing
- Health Surveys
- Humans
- Male
- Middle Aged
- Neoplasms
- Phenotype