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Article

Alcohol and aldehyde dehydrogenase polymorphisms and a new strategy for prevention and screening for cancer in the upper aerodigestive tract in East Asians.

The Keio journal of medicine - 1 Jan 2010

Yokoyama Akira, Omori Tai, Yokoyama Tetsuji

Abstract excerpt

The ethanol in alcoholic beverages and the acetaldehyde associated with alcohol consumption are Group 1 human carcinogens (WHO, International Agency for Research on Cancer). The combination of alcohol consumption, tobacco smoking, the inactive heterozygous aldehyde dehydrogenase-2 genotype (ALDH2*1/*2) and the less-active homozygous alcohol dehydrogenase-1B genotype (ADH1B*1/*1) increases the risk of squamous...

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Source

Identifiers

PMID: 21187698
DOI: 10.2302/kjm.59.115

Genes

ALDH2

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