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Article

Endoscopic screening using esophageal iodine staining and genotypes of ADH1B and ALDH2 in Japanese alcohol-dependent women.

PloS one - 1 Jan 2019

Yokoyama Akira, Yokoyama Tetsuji, Omori Tai, Maesato Hitoshi, Takimura Tsuyoshi, Iwahara Chie, Kimura Mitsuru, Matsui Toshifumi, Mizukami Takeshi, Maruyama Katsuya

Abstract excerpt

BACKGROUND: The presence of large or multiple esophageal distinct iodine-unstained lesions (DIULs) is a strong predictor of field cancerization in the upper aerodigestive tract. Several risk factors for DIULs, including genetic polymorphisms of alcohol and aldehyde dehydrogenases (ADH1B, rs1229984; ALDH2, rs671), have been demonstrated in Japanese alcohol-dependent men. However, few evaluations of...

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Source

Open in PubMed Open full text

Identifiers

PMID: 30629674
DOI: 10.1371/journal.pone.0210546
PMCID: PMC6328133

Genes

ALDH2
ADH1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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