Evaluation of the use of self-reported facial flushing and ethanol patch test for ALDH2 genotypes.

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Article

Evaluation of the use of self-reported facial flushing and ethanol patch test for ALDH2 genotypes.

Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence - 1 Oct 2010

Ishibashi Tokuo, Taguchi Ayako, Yamamoto Yasushi, Harada Shoji

Abstract excerpt

It is generally assumed that subjects with ALDH2*1/1 do not exhibit flushing symptoms after alcohol intake, but recent studies have revealed discordance in ALDH2 genotypes with self-reported facial flushing and the ethanol patch test. We evaluated the reliability of a facial flushing questionnaire and the ethanol patch test in 495 Japanese volunteers. Genomic DNA was extracted from peripheral blood samples and...

Topics

Adult
Alcohol Drinking
Aldehyde Dehydrogenase
Aldehyde Dehydrogenase, Mitochondrial
Asian People
Ethanol
Face
Female
Flushing
Genotype
Humans
Male
Middle Aged
Patch Tests
Polymerase Chain Reaction
Polymorphism, Genetic
Reproducibility of Results
Surveys and Questionnaires

Source

Open in PubMed

Identifiers

PMID: 21222353

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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