Article
Evaluation of the use of self-reported facial flushing and ethanol patch test for ALDH2 genotypes.
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence - 1 Oct 2010
Ishibashi Tokuo, Taguchi Ayako, Yamamoto Yasushi, Harada Shoji
Abstract excerpt
It is generally assumed that subjects with ALDH2*1/1 do not exhibit flushing symptoms after alcohol intake, but recent studies have revealed discordance in ALDH2 genotypes with self-reported facial flushing and the ethanol patch test. We evaluated the reliability of a facial flushing questionnaire and the ethanol patch test in 495 Japanese volunteers. Genomic DNA was extracted from peripheral blood samples and...
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