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Article

Phenotypic and genotypic characteristics of aberrant crypt foci in human colorectal mucosa.

Human pathology - 1 Dec 1997

Nucci M R, Robinson C R, Longo P, Campbell P, Hamilton S R

Abstract excerpt

Aberrant crypt foci (ACF) in colorectal mucosa are proposed to be the earliest morphological lesion in the development of neoplasia, but their characteristics remain controversial. We therefore studied the epithelial phenotype and genotype of ACF from patients with familial adenomatous polyposis (FAP) and of sporadic ACF by evaluating glycoprotein markers associated with neoplasia (lectins Dolichus biflorus...

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PMID: 9416697
DOI: 10.1016/s0046-8177(97)90230-6

Genes

FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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