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Article

Dysplastic Aberrant Crypt Foci: Biomarkers of Early Colorectal Neoplasia and Response to Preventive Intervention.

Cancer prevention research (Philadelphia, Pa.) - 1 Mar 2020

Clapper Margie L, Chang Wen-Chi L, Cooper Harry S

Abstract excerpt

The discovery of aberrant crypt foci (ACF) more than three decades ago not only enhanced our understanding of how colorectal tumors form, but provided new opportunities to detect lesions prior to adenoma development and intervene in the colorectal carcinogenesis process even earlier. Because not all ACF progress to neoplasia, it is important to stratify these lesions based on the presence of dysplasia and...

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Identifiers

PMID: 32132117
DOI: 10.1158/1940-6207.CAPR-19-0316
PMCID: PMC7080315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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