Article
A rat alveolar type II cell line developed by adenovirus 12SE1A gene transfer.
American journal of respiratory cell and molecular biology - 1 Jan 1992
Steele M P, Levine R A, Joyce-Brady M, Brody J S
Abstract excerpt
The regulation of pulmonary alveolar type II cell proliferation and differentiation is poorly understood and has been difficult to study, in part due to lack of proliferation, cellular heterogeneity, and phenotypic instability of type II cells in primary culture. To develop a stable population of homogeneous cells capable of proliferation, we transfected type II cells isolated from the lungs of neonatal rats with...
Topics
- Adenoviridae
- Animals
- Cell Differentiation
- Cell Division
- Cell Line
- Cell Separation
- Clone Cells
- Epithelial Cells
- Genes, Viral
- Phenotype
- Phospholipids
- Pulmonary Alveoli