Article
Differential expression of a V-type ATPase C subunit gene, Atp6v1c2, during culture of rat lung type II pneumocytes.
Journal of biomedical science - 1 Dec 2005
Feng Nan-Hsiung, Lin Hen-I, Wang Jinn-Shyan, Chou Shao-Ting, Ma Hon-Kwong, Rooney Seamus A, Lu Jyh-Feng
Abstract excerpt
The lung alveolar epithelium consists of type I and type II pneumocytes. In vivo, the type II cell is the progenitor cell from which the type I cell originates. When freshly-isolated type II cells are cultured under conventional conditions they rapidly lose their phenotypic properties and attain characteristics of type I cells. Taking advantage of this transdifferentiation, we sought to identify genes that are...
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