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Article

Angiotensin converting enzyme insertion/deletion polymorphism and short-term renal response to ACE inhibition: role of sodium status.

Kidney international. Supplement - 1 Dec 1997

van der Kleij F G, Schmidt A, Navis G J, Haas M, Yilmaz N, de Jong P E, Mayer G, de Zeeuw D

Abstract excerpt

Angiotensin converting enzyme (ACEi) inhibition retards renal function loss, but the therapeutic benefit varies between individuals. Renoprotection is poor in patients with the ACE DD genotype. ACE genotype is reported to affect short-term antiproteinuric response to ACEi, a predictor of long-term renoprotection, in some studies but not in others. Short-term responses to ACEi are enhanced by stimulating the...

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Source

Identifiers

PMID: 9407415

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Angiotensin converting enzyme insertion/deletion polymorphism and short-term renal response to ACE inhibition: role of sodium status.PMID 9407415Read ↗

ACE polymorphism does not determine short-term renal response to ACE-inhibition in proteinuric patients.Semantic proximity Read ↗

Antiproteinuric effect of losartan in non-diabetic renal disease is not dependent on ACE insertion/deletion polymorphism.Semantic proximity Read ↗

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ACE insertion/deletion polymorphism and diabetic nephropathy: clinical implications of genetic information.Semantic proximity Read ↗

Long-term renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype?Semantic proximity Read ↗

Time to consider ACE insertion/deletion genotypes and individual renoprotective treatment in diabetic nephropathy?Semantic proximity Read ↗

Response to angiotensin-converting enzyme inhibition is selectively blunted by high sodium in angiotensin-converting enzyme DD genotype: evidence for gene-environment interaction in healthy volunteers.Semantic proximity Read ↗

Renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype?Semantic proximity Read ↗

Angiotensin converting enzyme gene polymorphism and ACE inhibition in diabetic nephropathy.Semantic proximity Read ↗

Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies.Semantic proximity Read ↗

Enhanced responses of blood pressure, renal function, and aldosterone to angiotensin I in the DD genotype are blunted by low sodium intake.Semantic proximity Read ↗

Different Mechanisms for the Progression of CKD with ACE Gene Polymorphisms.Semantic proximity Read ↗

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