Article
ACE polymorphism does not determine short-term renal response to ACE-inhibition in proteinuric patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 1997
van der Kleij F G, Navis G J, Gansevoort R T, Heeg J E, Scheffer H, de Zeeuw D, de Jong P E
Abstract excerpt
BACKGROUND: The renal response to ACE inhibition is known to vary between individuals. The ACE genotype is a determinant of the ACE concentrations in plasma and tissue, and therefore might affect the renal response to ACE inhibition in renal patients. METHODS: To test this hypothesis we studied the short-term response to ACE inhibition (enalapril or lisinopril 10/20 mg/d) in 61 stable proteinuric patients (> 1.0...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.