Article
Angiotensin converting enzyme gene polymorphism and ACE inhibition in diabetic nephropathy.
Kidney international - 1 Apr 1998
Jacobsen P, Rossing K, Rossing P, Tarnow L, Mallet C, Poirier O, Cambien F, Parving H H
Abstract excerpt
The antiproteinuric effect of angiotensin converting enzyme (ACE) inhibition in insulin-dependent diabetes mellitus (IDDM) patients with diabetic nephropathy varies considerably. Therefore, we tested the potential role of an insertion (I)/deletion (D) polymorphism of the ACE gene on this early an...
Topics
- Adult
- Albuminuria
- Angiotensin-Converting Enzyme Inhibitors
- Diabetes Mellitus, Type 1
- Diabetic Nephropathies
- Female
- Follow-Up Studies
- Genotype
- Humans
- Male
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- Regression Analysis