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Article

Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies.

Clinical journal of the American Society of Nephrology : CJASN - 1 Sept 2008

Ruggenenti Piero, Bettinaglio Paola, Pinares Franck, Remuzzi Giuseppe

Abstract excerpt

Despite the huge amount of studies looking for candidate genes, the ACE gene remains the unique, well-characterized locus clearly associated with pathogenesis and progression of chronic kidney disease, and with response to treatment with drugs that directly interfere with the renin angiotensin system (RAS), such as angiotensin converting enzyme (ACE) inhibitors and angiotensin II receptor antagonists (ARA). The...

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Source

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Identifiers

PMID: 18550651
DOI: 10.2215/CJN.04140907
PMCID: PMC4571148

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies.PMID 18550651Read ↗

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