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Article

ACE insertion/deletion polymorphism and diabetic nephropathy: clinical implications of genetic information.

Journal of diabetes research - 1 Jan 2014

Ha Sung-Kyu

Abstract excerpt

Approximately 20-40% of diabetic patients develop nephropathy which is the leading cause of ESRD in developed countries. The ACE I/D polymorphism is thought to be a marker for functional polymorphism which regulates circulating and tissue ACE activity. While the initial study found a protective effect of the II genotype on the development of nephropathy in IDDM patients, subsequent studies have addressed the role...

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Share to Angiotensin-Converting Enzyme Inhibitors
Share to Angiotensin II Type 1 Receptor Blockers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

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Share to Kidney Failure, Chronic

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Source

Open in PubMed Open full text

Identifiers

PMID: 25587546
DOI: 10.1155/2014/846068
PMCID: PMC4284953

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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