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Article

Long-term renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype?

Diabetes care - 1 May 2003

Andersen Steen, Tarnow Lise, Cambien Francois, Rossing Peter, Juhl Tina R, Deinum Jaap, Parving Hans-Henrik

Abstract excerpt

OBJECTIVE: Several observational follow-up studies have found that the D allele of the insertion (I)/deletion (D) polymorphism of the ACE gene (ACE/ID) is associated with an increased risk of renal function loss, even during ACE inhibition. Therefore, we investigated the long-term effect of the angiotensin II subtype-1 (AT1) receptor antagonist losartan (100 mg o.d.) on kidney function in II and DD type 1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12716812
DOI: 10.2337/diacare.26.5.1501

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Long-term renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype?PMID 12716812Read ↗

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