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Article

ACE genotype and ACE inhibitor response in kidney disease: a perspective.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Aug 2002

Mayer Gert

Abstract excerpt

Angiotensin-converting enzyme (ACE) inhibitors have been shown to reduce blood pressure and slow the progression of renal diseases. However, a substantial interindividual variability in treatment response also has been noted. The activity of ACE is partially dependent on the presence or absence of a 287-bp element in intron 16, and this insertion/deletion (I/D) polymorphism accounts for 47% of the total...

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Source

Identifiers

PMID: 12148094
DOI: 10.1053/ajkd.2002.34489

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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