Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different Mechanisms for the Progression of CKD with ACE Gene Polymorphisms.

Nephron. Clinical practice - 1 Jan 2009

Nakayama Yushi, Nonoguchi Hiroshi, Kohda Yukimasa, Inoue Hideki, Memetimin Hasiyet, Izumi Yuichiro, Tomita Kimio

Abstract excerpt

BACKGROUND/AIMS: The blockade of the renin-angiotensin-aldosterone system is the major target of efforts to prevent the progression of chronic kidney disease (CKD). Dual blockade with angiotensin-converting enzyme (ACE) inhibitor and angiotensin II receptor blocker has been reported to show additive renoprotection. However, three types of insertion/deletion (I/D) polymorphism have been reported, and it is unclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to ACE gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Failure, Chronic

Share to Polymorphism, Single Nucleotide

Share to Proteinuria

Source

Identifiers

PMID: 19293592
DOI: 10.1159/000209150

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different Mechanisms for the Progression of CKD with ACE Gene Polymorphisms.PMID 19293592Read ↗

ACE insertion/deletion polymorphism and diabetic nephropathy: clinical implications of genetic information.Semantic proximity Read ↗

Meta-analysis of the relationship between ACE I/D gene polymorphism and end-stage renal disease in patients with diabetic nephropathy.Semantic proximity Read ↗

The association of ACE gene polymorphism with diabetic kidney disease and renoprotective efficacy of valsartan.Semantic proximity Read ↗

Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies.Semantic proximity Read ↗

The impact of angiotensin converting enzyme insertion/deletion gene polymorphism on diabetic kidney disease: A debatable issue.Semantic proximity Read ↗

Antiproteinuric effect of losartan in non-diabetic renal disease is not dependent on ACE insertion/deletion polymorphism.Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion polymorphism contributes high risk for chronic kidney disease in Asian male with hypertension--a meta-regression analysis of 98 observational studies.Semantic proximity Read ↗

Association between angiotensin-converting enzyme insertion/deletion gene polymorphism and end-stage renal disease susceptibilitySemantic proximity Read ↗

A meta-analysis of the association between angiotensin-converting enzyme insertion/deletion gene polymorphism and end-stage renal disease risk in IgA nephropathy patients.Semantic proximity Read ↗

ACE gene polymorphism and progression of diabetic nephropathy in Korean type 2 diabetic patients: effect of ACE gene DD on the progression of diabetic nephropathy.Semantic proximity Read ↗

Association between the <i>ACE</i> I/D gene polymorphism and progressive renal failure in autosomal dominant polycystic kidney disease: A meta-analysisSemantic proximity Read ↗

Angiotensin-converting enzyme gene I/D polymorphism and renal disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.