Article
X-ray structure of motor and neck domains from rat brain kinesin.
Biochemistry - 23 Dec 1997
Sack S, Müller J, Marx A, Thormählen M, Mandelkow E M, Brady S T, Mandelkow E
Abstract excerpt
We have determined the X-ray structure of rat kinesin head and neck domains. The folding of the core motor domain resembles that of human kinesin reported recently [Kull, F. J., et al. (1996) Nature 380, 550-554]. Novel features of the structure include the N-terminal region, folded as a beta-strand, and the C-terminal transition from the motor to the rod domain, folded as two beta-strands plus an alpha-helix....
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