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Article

Determinants of kinesin motor polarity.

Science (New York, N.Y.) - 21 Aug 1998

Endow S A, Waligora K W

Abstract excerpt

The kinesin motor protein family members move along microtubules with characteristic polarity. Chimeric motors containing the stalk and neck of the minus-end-directed motor, Ncd, fused to the motor domain of plus-end-directed kinesin were analyzed. The Ncd stalk and neck reversed kinesin motor polarity, but mutation of the Ncd neck reverted the chimeric motor to plus-end movement. Thus, residues or regions...

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Source

Identifiers

PMID: 9712586
DOI: 10.1126/science.281.5380.1200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Determinants of kinesin motor polarity.PMID 9712586Read ↗

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A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd.Semantic proximity Read ↗

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