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Article

Regulation of plasmid R1 replication: PcnB and RNase E expedite the decay of the antisense RNA, CopA.

Molecular microbiology - 1 Nov 1997

Söderbom F, Binnie U, Masters M, Wagner E G

Abstract excerpt

The replication frequency of plasmid R1 is controlled by an unstable antisense RNA, CopA, which, by binding to its complementary target, blocks translation of the replication rate-limiting protein RepA. Since the degree of inhibition is directly correlated with the intracellular concentration of CopA, factors affecting CopA turnover can also alter plasmid copy number. We show here that PcnB (PAPl-a...

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PMID: 9402020
DOI: 10.1046/j.1365-2958.1997.5871953.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Regulation of plasmid R1 replication: PcnB and RNase E expedite the decay of the antisense RNA, CopA.PMID 9402020Read ↗

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