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Article

The Escherichia coli pcnB gene promotes adenylylation of antisense RNAI of ColE1-type plasmids in vivo and degradation of RNAI decay intermediates.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1993

Xu F, Lin-Chao S, Cohen S N

Abstract excerpt

Previous work has shown that RNase E-mediated cleavage of RNAI, an antisense repressor of the replication of ColE1-type plasmids, relieves repression in vivo by endonucleolytically converting RNAI to a rapidly decaying product. We report that mutations in the Escherichia coli pcnB gene result in a 10-fold prolongation of the half-life of RNAI decay intermediates and also of truncated RNAI primary transcripts...

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Identifiers

PMID: 7688127
DOI: 10.1073/pnas.90.14.6756
PMCID: PMC47011

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The Escherichia coli pcnB gene promotes adenylylation of antisense RNAI of ColE1-type plasmids in vivo and degradation of RNAI decay intermediates.PMID 7688127Read ↗

RNA degradation in Escherichia coli regulated by 3' adenylation and 5' phosphorylation.Semantic proximity Read ↗

Absence of RNASE III alters the pathway by which RNAI, the antisense inhibitor of ColE1 replication, decays.Semantic proximity Read ↗

Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1.Semantic proximity Read ↗

The effects of RNA degradation enzymes on antisense RNAI controlling ColE2 plasmid copy number.Semantic proximity Read ↗

Regulation of plasmid R1 replication: PcnB and RNase E expedite the decay of the antisense RNA, CopA.Semantic proximity Read ↗

Rapid degradation of polyadenylated oop RNA.Semantic proximity Read ↗

Replication initiator protein mRNA of ColE2 plasmid and its antisense regulator RNA are under the control of different degradation pathways.Semantic proximity Read ↗

The pcnB gene of Escherichia coli, which is required for ColE1 copy number maintenance, is dispensable.Semantic proximity Read ↗

Residual polyadenylation in poly(A) polymerase I (pcnB ) mutants of Escherichia coli does not result from the activity encoded by the f310 gene.Semantic proximity Read ↗

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