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Article

The Escherichia coli pcnB gene promotes adenylylation of antisense RNAI of ColE1-type plasmids in vivo and degradation of RNAI decay intermediates.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1993

Xu F, Lin-Chao S, Cohen S N

Abstract excerpt

Previous work has shown that RNase E-mediated cleavage of RNAI, an antisense repressor of the replication of ColE1-type plasmids, relieves repression in vivo by endonucleolytically converting RNAI to a rapidly decaying product. We report that mutations in the Escherichia coli pcnB gene result in...

Topics

Adenosine Monophosphate
Bacterial Proteins
Bacteriocin Plasmids
Base Sequence
Endoribonucleases
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Genetic Variation
Half-Life
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polynucleotide Adenylyltransferase

RNA, Antisense

RNA, Bacterial

Sequence Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 7688127
DOI: 10.1073/pnas.90.14.6756
PMCID: PMC47011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7688127-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The Escherichia coli pcnB gene promotes adenylylation of antisense RNAI of ColE1-type plasmids in vivo and degradation of RNAI decay intermediates.PMID 7688127Read ↗

RNA degradation in Escherichia coli regulated by 3' adenylation and 5' phosphorylation.Semantic proximity Read ↗

Absence of RNASE III alters the pathway by which RNAI, the antisense inhibitor of ColE1 replication, decays.Semantic proximity Read ↗

Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1.Semantic proximity Read ↗

The effects of RNA degradation enzymes on antisense RNAI controlling ColE2 plasmid copy number.Semantic proximity Read ↗

Regulation of plasmid R1 replication: PcnB and RNase E expedite the decay of the antisense RNA, CopA.Semantic proximity Read ↗

Rapid degradation of polyadenylated oop RNA.Semantic proximity Read ↗

Replication initiator protein mRNA of ColE2 plasmid and its antisense regulator RNA are under the control of different degradation pathways.Semantic proximity Read ↗

The pcnB gene of Escherichia coli, which is required for ColE1 copy number maintenance, is dispensable.Semantic proximity Read ↗

Residual polyadenylation in poly(A) polymerase I (pcnB ) mutants of Escherichia coli does not result from the activity encoded by the f310 gene.Semantic proximity Read ↗

An unusually long-lived antisense RNA in plasmid copy number control: in vivo RNAs encoded by the streptococcal plasmid pIP501.Semantic proximity Read ↗

Initial events in the degradation of the polycistronic puf mRNA in Rhodobacter capsulatus and consequences for further processing steps.Semantic proximity Read ↗

Evidence in vivo that the DEAD-box RNA helicase RhlB facilitates the degradation of ribosome-free mRNA by RNase E.Semantic proximity Read ↗

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